Histological and Immunohistochemical Changes in Facial Skin Treated with Combined Ablative and Non‐Ablative Laser Therapy

N.A. Shanina, A.V. Patrushev, A. Zorman
Journal of Cosmetic Dermatology (2021), doi.org/10.1111/jocd.14023

Abstract

Purpose of the study

The objective of this study was to evaluate the macroscopic and histological and immunohistochemical changes in facial skin treated with a combined laser therapy.

Material and methods

Fourteen patients aged from 38 to 59 years were included in the study. Two different wavelengths (2940 and 1064 nm) were used in this four‐step procedure.

Results

Significant improvement according to classification for age‐related changes in all areas of the face was achieved. There were also significant structural changes in the epidermis and dermis, confirmed with histology and immunohistochemistry.

Conclusions

The dual‐wavelength protocol has been found to provide excellent results for facial rejuvenation.

Histological and Immunohistochemical Changes in Facial Skin Treated with Combined Ablative and Non‐Ablative Laser Therapy

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